홍승환

Professor

Hong, Seung Hwan

홍승환
Research
Cell Biology
1. Study for genes regulated by STAT3 transcription factor
● Identification of STAT3-downstream genes in embryonic stem (ES) cells
● Search for the function of STAT3-downstream genes in ES cells
● Self-renewal and differentiation of ES cells
2. cAMP-signaling pathways during growth inhibition and apoptosis in cancer cells
● Anticancer activity of 8-Cl-cAMP
● Cross-talk of cAMP signaling with other pathways : PKC, AMPK, MAPK, Rap1 etc.
Education/Career
Education
  • - 1985.2 - 1987.5 Ph.D. : Albert Einstein College of Med
  • - 1982.2 - 1985.1 Master : Albert Einstein College of Med
  • - 1978.3 - 1981.2 Master : Seoul National University
  • - 1974.3 - 1978.2 Bachelor : Seoul National University
Career
  • - 2008 - 2008 Dean of Academic Affairs, College of Natural Sciences, Seoul National University
  • - 2007 - 2008 Chief of Planning, College of Natural Sciences, Seoul National University
  • - 2006 - 2007 Head of Medical Preparation Department, College of Natural Sciences, Seoul National University
  • - 2006 - 2007 Head of Veterinary Preparation Department, College of Natural Sciences, Seoul National University
  • - 2003 - 2005 Head of Basic Sciences Education Research Common Equipment, Seoul National University
  • - 2001 - 2003 분자세포생물학연구소장 기초과학
Publications
  1. Han, JH, Ahn YH, Choi Y, Hong SH (2009) Involvement of AMP-Activated Protein Kinase and p38 Mitogen-Activated Protein Kinase in 8-Cl-cAMP-Induced Growth Inhibition. J Cell Physiol 218: 104-112.
  2. Ahn YH, Han JH, Hong SH (2006) Rap1 and p38 MAPK Mediate 8-Chloro-cAMP-Induced Growth Inhibition in Mouse Fibroblast DT Cells. J Cell Physiol 209: 1039-1045.
  3. Ko SY, Kang HY, Lee HS, Han SY, Hong SH (2006) Identification of Jmjd1a as a STAT3 Downstream Gene in mES Cells. Cell Struct Funct 31: 53-62.
  4. Kim SG, Kim HA, Jong HS, Park JH, Kim NK, Hong SH, Kim TY, Bang YJ (2005) The endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3. Mol Biol Cell 16: 4672-4683.
  5. Ahn YH, Jung JM, Hong SH (2005) 8-Chloro-cyclic AMP-induced growth inhibition and apoptosis is mediated by p38 mitogen-activated protein kinase activation in HL60 cells. Cancer Res 65: 4896-4901.