Postdoc Positions 모집공고 (Dr. Yi Zhang’s lab at Harvard Medical School and Boston Children’s Hospital)
10월 28일 11시에 세미나를 하는 Yi Zhang 교수의 post-doc. 모집 광고입니다.
관심있는 분들의 많은 지원바랍니다.
Postdoc Positions available in Dr. Yi Zhang’s lab at Harvard Medical School and Boston Children’s Hospital
The Zhang lab has recently relocated to Harvard Medical School and Boston Children’s Hospital. In association with the move and lab expansion, several postdoc positions are available.
The current lab interests are centered on understanding the mechanism and function of epigenetic regulation in stem cell, reprogramming, and brain functions.
The lab is interested in recruiting ambitious and highly motivated postdoctoral research associates to participate in the cutting age research in one of the following areas:
1) Developing new techniques for single cell analysis of DNA methylation and locusspecific histone modification studies;
2) Investigating the molecular mechanism of egg-mediated reprogramming;
3) Investigating the epigenetic mechanism of mouse preimplantation development with the emphasis on the earliest events that lead to the first cell lineage commitment;
4) Investigating the epigenetic contribution to brain learning and memory as well as reward related addiction;
5) Identification and characterization of new epigenetic modifications.
Previous experience in preimplantation embryo manipulation, micro-injection, neurobiology related areas or bioinformatics is preferred, but not required. Interested person should visit the lab web site http://zhanglab.tch.harvard.edu/lab.htm and send your application to Dr. Yi Zhang (yzhang@genetics.med.harvard.edu).
Some of the representative publications from the Zhang lab are as follows:
1. Wu, H., et al (2011). Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 473, 389-93.
2. Ito, S., et al (2011). Tet proteins can convert 5-methylcytosine to 5-formalcytosine and 5-carboxylcytosine. Science 333, 1300-03.
3. Inoue, A., and Zhang, Y. (2011). Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science 334, 194.
4. Yamaguchi, S., et al (2012). Tet1 controls meiosis by regulating meiotic gene expression. Nature 492, 443-447.
5. He, J., et al (2013). Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of early lineage genes. Nat. Cell Biol 15, 373-384.
6. Shen, L., et al (2013). Genome-wide analysis reveals TET and TDG-mediated 5-methylcytosine oxidation dynamics. Cell 153, 692-706.
7. Ran, F.A., et al (2013). Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell 154, 1380-1389.