김재범

김재범

교수
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김재범

교수

김재범 Kim, Jae Bum

김재범
연구분야
분자생물학 세포생물학 유전학
1. Mechanism of Adipocyte Differentiation
2. Gene Expression Regulation of Lipogenesis and Insulin-dependent Genes
3. Molecular Mechanisms for Obesity and Diabetes
학력/경력
학력
  • - 1984 - 1988 서울대학교 자연대학 동물학과 학사
  • - 1988 - 1990 서울대학교 자연대학 동물학과 (분자생물학 전공) 석사
  • - 1991 - 1996 하버드대학교 분자유전학 박사
경력
  • - 1996 - 1997 하버드대학교 Dana-Farber Cancer Institute 박사후연구원
  • - 1997 - 2000 MIT Cancer Institute 박사후연구원
  • - 2000 - Present 서울대학교 생명과학부 조교수, 부교수, 정교수
  • - 2004 - Present 한국과학기술한림원 준회원, 정회원
  • - 2005 - 2008 보건복지부 국가생명윤리심의위원회 전문위원
  • - 2007 - 2008 Univ. of California, San Diego 초빙교수
  • - 2009 - 2011 서울대학교 실험동물자원관리원장
  • - 2010 - 2014 서울대학교 SPARC 부주임교수
  • - 2011 - 2012 서울대학교 유전공학연구소장
  • - 2011 - 2020 지방조직 리모델링 창의연구단 단장
  • - 2013 - 2014 국가과학기술자문위원회 자문위원
  • - 2014 - 2015 Univ. of California, Los Angeles 초빙교수
  • - 2020 - Present 지방세포 구조-기능 리더연구단장
  • - 2021 - 2023 한국분자세포생물학회지 (Molecules and Cells) 편집위원장 (Editor-in-Chief)
  • - 2021 - 2023 서울대학교 생명과학부 학부장
주요논문
  1. J. Kong, Y. Ji, Y. G. Jeon, J. S. Han, K. H. Han, J. H. Lee, G. Lee, H. Jang, S. S. Choe, M. Baes, and J. B. Kim*. Spatiotemporal contact between peroxisome and lipid droplet regulates fasting-induced lipolysis via PEX5. Nat Commun., 11(1):578, 2020. 01.
  2. Y. J. Park, S. Lee, S. Lim, H. Nahmgoong, Y. Ji, J. Y. Huh, A. A. Alfadda, S. Kim, and J. B. Kim*. Dnmt1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondria dynamics. Proc. Natl. Acad. Sci., 118(11): e2021073118, 2021. 03. (This paper is highlighted in the ‘Commentary’ in Proc. Natl. Acad. Sci. 2021 118 (15) e2102944118)
  3. J. H. Sohn, Y. Ji, C. Cho, H. Nahmgoong, S. Lim, Y. G. Jeon, S. M. Han, J. S. Park, I. Rhee, H. Kim, S. Kim, and J. B. Kim*. Spatial regulation of reactive oxygen species via G6PD in nrown adipocytes Supports thermogenic function. Diabetes, 70:22756-70, 2021. 12. (In the same issue, cover figure is selected from this paper.)
  4. H. Nahmgoong, Y. G. Jeon, E. S. Park, Y. H. Choi, S. M. Han, J. Park, Y. Ji, J. H. Sohn, J. S. Han, Y. Y. Kim, I. J. Hwang, Y. K. Lee, J. Y. Huh, S. S. Choe, T. J. Oh, S. H. Choi, J. K. Kim, and J. B. Kim*. Distinct properties of adipose stem cell subpopulations determine fat depot-specific characteristics. Cell Metab., 34:458-472, 2022. 03. (This study is highlighted on the cover figure. This paper is highlighted in Nat. Rev. Endocrinol. 18:133 [2022])
  5. G. Lee, Y. Y. Kim, H. Jang, J. S. Han, H. Nahmgoong, Y. J. Park, S. M. Han, C. Cho, S. Lim, J. Noh, W. K. Oh, C. Lee, S. Kim, and J. B. Kim*. SREBP1c-PARP1 axis tunes anti-senescence activity of adipocytes and ameliorates metabolic imbalance in obesity. Cell Metab., 34:702-718, 2022. 05. (This paper is introduced as ‘research highlights’ in Nat. Cell Biol. 24:601 [2022])
  6. J. S. Han, Y. G. Jeon, M. Oh, G. Lee, H. Nahmgoong, S. M. Han, Y. Y. Kim, K. C. Shin, J. Kim, K. Jo, S. S. Choe, E. J. Park, S. Kim, and J. B. Kim*. Adipocyte HIF2alpha functions as a thermostat via PKA Cα regulation in beige adipocytes. Nat. Commun., 13:3268, 2022. 06.
  7. J. Park, D. H. Lee, S. Ham, J. Oh, J. Noh, Y. K. Lee, Y. J. Park, G. Lee, S. M. Han, J. S. Han, Y. Y. Kim, Y. G. Jeon, H. Nahmgoong, K. C. Shin, S. M. Kim, S. H. Choi, C. Lee, J. Park, T. Y. Roh, S. Kim, and J. B. Kim*. Targeted erasing of DNA methylation drives adipogenic reprogramming. Nat. Metab., 4(7):918-931, 2022.07.
  8. Y. G. Jeon, Y. Y. Kim, G. Lee, J. B. Kim*. Physiological and pathological roles of lipogenesis. Nat. Metab., 5:735-759, 2023.05
  9. S. M. Han, E. S. Park, J. Park, H. Nahmgoong, Y. H. Choi, J. Oh, K. M. Yim, W. T. Lee, Y. G. Jeon, K. C. Shin, J. Y. Huh, S. H. Choi, J. Park, J. K. Kim, and J. B. Kim*. Unique adipose tissue invariant natural killer T cell subpopulations control adipocyte turnover in mice. Nat. Commun. 14:8512, 2023.12.
  10. Y. G. Jeon, H. Nahmgoong, J. Oh, D. Lee, D. W. Kim, J. E. Kim, Y. Y. Kim, Y. Ji, J. S. Han, S. M. Kim, J. H. Sohn, W. T. Lee, S. W. Kim, J. Park, J. Y. Huh, K. Jo, J-Y Cho, J. Park, and J. B. Kim*. Ubiquitin Ligase RNF20 Coordinates Sequential Adipose Thermogenesis with Brown and Beige Fat-Specific Substrates. Nat. Commun, 15:940, 2024.01.
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