교수
석영재 Seok, Yeong-Jae
연구분야
미생물학
생화학
1. Glucose signaling in bacteria
● New roles of PTS proteins in E. coli and V. vulnificus
● Regulation of PTS expression by glucose and other metabolites
2. Bacterial pathogenesis
● Roles of PTS proteins in bacterial pathogenesis
● Ligand fishing of new factors affecting bacterial pathogenesis
3. Exploration of new bacterial signaling systems
● Functional study of the nitrogen-metabolic PTS
● Elucidation of targets regulated by the new phosphotransferase system
4. Regulation of global gene expression in bacteria
● Mechanisms on carbon catabolite repression in Gram-negative bacteria
● Regulation of global gene expression by the nitrogen-metabolic PTS
● New roles of PTS proteins in E. coli and V. vulnificus
● Regulation of PTS expression by glucose and other metabolites
2. Bacterial pathogenesis
● Roles of PTS proteins in bacterial pathogenesis
● Ligand fishing of new factors affecting bacterial pathogenesis
3. Exploration of new bacterial signaling systems
● Functional study of the nitrogen-metabolic PTS
● Elucidation of targets regulated by the new phosphotransferase system
4. Regulation of global gene expression in bacteria
● Mechanisms on carbon catabolite repression in Gram-negative bacteria
● Regulation of global gene expression by the nitrogen-metabolic PTS
학력/경력
학력
- - 1987.3-199.2 박사: 서울대학교 대학원 미생물학과
- - 1985.3-1987.2 석사: 서울대학교 대학원 미생물학과
- - 1981.3-1985.2 학사: 서울대학교 미생물학과
경력
- - 2015-현재 한국미생물학회 실무위원장, 출판위원장, 이사
- - 2014.07-2017.02 서울대학교 생물물리 및 화학생물학과 학과장
- - 2010.11-2012.10 서울대학교 자연과학대학 교무부학장
- - 2005.03-2009.03 서울대학교 미생물연구소장
- - 2007.04- 현재 교수 서울대학교 생명과학부
- - 2001.10-2007.03 부교수 서울대학교 생명과학부
- - 1997.09-2001.09 조교수 서울대학교 미생물학과
- - 1994-1997 미국 National Institutes of Health 박사후연구원
주요논문
- Kim HM, Yoon CK, Ham HI, Seok YJ*, Park YH* (2018) Stimulation of Vibrio vulnificus pyruvate kinase in the presence of glucose to cope with H2O2 stress generated by its competitors. Frontiers in Microbiology 9: 1112
- Lee JW, Park YH, Seok YJ (2018) Rsd balances (p)ppGpp level by stimulating the hydrolase activity of SpoT during carbon source downshift in Escherichia coli. Proc Natl Acad Sci USA 115(29): E6845-E6854.
- Lee CR, Park YH, Kim YR, Seok YJ (2019) Determination of protein phosphorylation by polyacrylamide gel electrophoresis. J Microbiol 57(2): 93-100.
- Park S, Yoon J, Lee CR, Lee JY, Kim YR, Jang KS, Lee KH, Seok YJ (2019) Polar landmark protein HubP recruits flagella assembly protein FapA under glucose limitation in Vibrio vulnificus. Mol Microbiol 112(1): 266-279
- Choe M, Min H, Park YH, Kim YR, Woo JS, Seok YJ (2019) Structural insight into glucose repression of the mannitol operon. Sci Rep 9: 13930
- Heo K, Park YH, Lee KA, Kim J, Ham HI, Kim BG, Lee WJ, Seok YJ (2019) Sugar-mediated regulation of a c-di-GMP phosphodiesterase in Vibrio cholerae. Nature Comm 10(1): 5358